Abstract Massive localized lymphedema (MLL) is a recently described clinical condition characterized by lymphedema resulting from focally disrupted lymphatic drainage in morbidly obese patients. These patients typically present with long-standing, painless, slow-growing, ill-defined soft tissue masses. The masses are often found in the inner thigh and may resemble liposarcoma both clinically and histologically. Due to its challenging imaging characteristics, MLL poses diagnostic difficulties for clinicians and pathologists. As the global obesity epidemic persists, the incidence of MLL is expected to rise, necessitating awareness and appropriate management strategies. In this context, we present a case of MLL affecting the thigh in a morbidly obese patient. The final diagnosis was given based on patient’s demographics and the presence of lymphedema in other parts of the body.
Keywords: lymphedema; liposarcoma; obesity; sarcoma; computed tomography