Abstract Protein electrophoresis is an easy, inexpensive test routinely used in clinical laboratories for screening protein abnormalities in various biological fluids. It is commonly used test to identify patients with multiple myeloma and other disorders of serum protein. Evaluation of patients with chronic kidney disease typically includes serum and urine protein electrophoresis. This retrospective study was undertaken to analyze the pattern of electrophoretic results at our exclusive nephrourology referral centre. All the patients who had been referred for electrophoresis (SPEP and UPEP) over the last two years (November 2012 to November 2014) were included in the study. A total of 1334 cases were referred for electrophoresis, out of which 830 samples were for serum protein electrophoresis. Major diseases diagnosed were infections/inflammation (42.4%), nephrotic syndrome (17.1%), liver disorders (7.1%), and multiple myeloma (6.4%). The main clinical presentation was acute renal failure preceding the diagnosis of myeloma. Hence it is necessary to look for potential renal impairment in myeloma patients.
Keywords: electrophoresis; renal failure; paraproteinemias; nephrotic syndrome; myeloma

Abstract We evaluated the changes in anatomical locations of endemic Burkitt’s lymphoma (eBL) by systematic review. We compared the reports before ultrasound became a routine investigation in Burkitt’s lymphoma (BL) diagnosis with those that used ultrasound as part of pre therapeutic diagnosis. Methods: All alternative match terms able to capture the anatomical distribution of eBL were used as search terms for two electronic databases, namely Medline and “Web of Science”. Only reports that had reasonable case load were considered for analysis. However the case reports and case series with five or less patients were not included. Results: Medline produced more systematic review identified reports. The search terms “endemic Burkitt lymphoma Africa” yielded the highest number of articles in both databases but had a low precision, at 3.5. Pattern of organ involvement Burkitt lymphoma Africa had a precision at 100%. Medline recalled 27 reports that were not recalled by the Web of Science. Generally it appears that studies that have relied on laparotomies, autopsies and ultrasound have reported a higher abdominal involvement in eBL than those using clinical examination and plain radiographs. This points to the possibility of missed abdominal involvement due to diagnostic techniques. Conclusion: the review confirms that as more Sub Saharan African (SSA) countries incorporate US as a routine investigation in management of eBL, we are likely to see more abdominal disease with or without facial manifestation.
Keywords: endemic Burkitt lymphoma; epidemiology; clinical picture; Bukitt’s lymphoma in Africa; diagnostic technology