Abstract Primary brain and CNS tumor incidence is approximately seven per 100,000 individuals per year worldwide. Glioblastoma multiforme metastasis outside the CNS are extremely rare, occurring in <2% of patients, so therapeutic experience with these types of tumors is limited. Extracranial bone metastasis arising from glioblastoma multiforme are uncommon and mechanism of their diffusion is not well known. We report the case of a man affected by a glioblastoma who had a dorsal spine metastasis without any brain relapse after excision of cerebral glioblastoma multiforme and adjuvant radio-chemotherapy.
Keywords: glioblastoma; metastasis; CNS tumor