Ethical Guidelines

All authors must warrant that their article is their own original work, which does not infringe the intellectual property rights of any other person or entity, and cannot be construed as plagiarizing any other published work, including their own previously published work.

NobleResearch Publishers follows the Committee of Publications Ethics (COPE). COPE aims to provide a forum for publishers and editors of scientific journals to discuss issues relating to the integrity of their work, including conflicts of interest, falsification and fabrication of data, plagiarism, unethical experimentation, inadequate subject consent, and authorship disputes.

For more information on COPE please visit http://publicationethics.org.

Authorship

Authorship confers credit and has important academic, social, and financial implications. Authorship also implies responsibility and accountability for published work. The following recommendations are intended to ensure that contributors who have made substantive intellectual contributions to a paper are given credit as authors, but also that contributors credited as authors understand their role in taking responsibility and being accountable for what is published.

The International Committee of Medical Journal Editors (ICMJE) recommends that authorship be based on the following 4 criteria:

• Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; and
• Drafting the work or revising it critically for important intellectual content; and
• Final approval of the version to be published; and
• Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Conflict of Interest

Articles should be published with statements or supporting documents, such as the ICMJE conflict of interest form, declaring:

• Authors’ conflicts of interest; and
• Sources of support for the work, including sponsor names along with explanations of the role of those sources if any in study design; collection, analysis, and interpretation of data; writing of the report; the decision to submit the report for publication; or a statement declaring that the supporting source had no such involvement; and
• Whether the authors had access to the study data, with an explanation of the nature and extent of access, including whether access is on-going.

Copyright

Copyright on any open access article in a journal published by NobleResearch Publishers is retained by the author(s).

The Creative Commons Attribution License 4.0 formalizes these and other terms and conditions of publishing articles. In accordance with our Open Data policy, the Creative Commons CC0 1.0 Public Domain Dedication waiver applies to all published data in NobleResearch Publishers open access articles. Please contact us if there are any questions regarding Copyright policy.

Categories of submission

Journal of Clinical Pharmacology and Toxicology accepts the following articles: case reports, editorial, letters to the editor, methodology, news and commentary, original research, rapid communications, review, short reports.

Acceptable file formats

Authors are asked to write their manuscripts in English and only electronic files conforming to the journal's guidelines will be accepted. Submissions should use a standard (non-narrow) 11-pt font such as Arial, Calibri, Times New Roman or Helvetica, have 1-inch margins on all sides and all text should be 1.5 spacing in between the lines. Footnotes should be used sparingly.

The manuscript text (including references, figure legends and simple tables) may be in .doc, .rtf or LaTeX format but preferred file format is Microsoft Word. Upload the main text file with the designation of "Manuscript file". If you submit your manuscript in LaTeX you must upload your source file and all other files (bib/sty/etc.). Zip all the supporting files in one single zip file for sending to the editorial office by email or through submission system.

Authors are encouraged to use the JCPT word template, Click here to download.

Organization and style of the manuscript

Articles should be divided into the following sections: Title page, Abstract/ Summary, Introduction, Results and Discussion, Materials and Methods (Methodology, Patients and methods, Subjects and methods, Experimental), Acknowledgements, Funding, References, Tables and Figure legends.

Title page

Concise titles are easier to read than long, convoluted ones. Titles that are too short may, however, lack important information, such as study design (which is particularly important in identifying randomized, controlled trials). Authors should include all information in the title that will make electronic retrieval of the article both sensitive and specific.

• Authors names and institutional affiliations, the name of the department(s) and institution(s) to which the work should be attributed.
• The name of corresponding author, complete postal addresses, telephone and fax numbers and email address of the author, responsible for correspondence of the manuscript.

Abstract and key words

The purpose of the abstract is twofold: (a) state the nature of the investigation and (b) summarize the important conclusions of this investigation. It should provide a brief summary of the research, including the purpose, methods, results, and major conclusions. The abstract should be suitable for separate publication in an abstract journal and be adequate for indexing.

• Abstract should be in a single paragraph and not exceed 250 words.
• Do not include literature citations in the abstract.
• The primary purpose of an abstract is to allow readers to determine quickly and easily the content and results of a paper.
• Provide up to 12 key words. Words from the title of the article may be included in the key words.
• Each key word should be useful as an entry point for a literature search.

Introduction: A brief introduction describing the manuscript significance should be intelligible to the general reader of the journal. The introduction should state the reason for doing the research work or hypotheses under consideration and essential background. The introduction is not a place for a lengthy review of the topic.

Materials and methods: It should provide sufficient information to allow someone to repeat your research work. A clear description of your experimental design, sampling methods, and statistical methods is especially important. If you list a product (e.g., glucose, amino acid analyzer), supply the name and location of the manufacturer, give the model number for equipment specified, supply complete citations, including author (or editor), title, year, publisher and version number.

Results and discussion:Results generally should be stated concisely and without interpretation, though in complex studies modest interpretation of individual parts can provide context helpful for understanding subsequent parts. The discussion should explain the significance of the results. Distinguish factual results from speculation and interpretation. Avoid excessive review.

Conclusions: Conclusions section is mandatory for the JHP. This should state clearly the main conclusions of the research and give a clear explanation of their importance and relevance.

Acknowledgments

Acknowledgments should be limited to collegial and financial assistance, such as a person who provided purely technical help, writing assistance, or a department chair who provided only general support should be listed in the acknowledgments.

Funding

Details of all funding agency names should be given in a separate section entitled 'Funding', i.e. 'National Institutes of Health funded' or not 'NIH'. Grant numbers should be given in square brackets as follows: [grant number xxxx]. Multiple grant numbers should be separated by a comma as follows: [grant numbers xxxx, yyyy]. If more than one agencies, they should be separated by a semi-colon (include 'and' before the last funding agency). Where individuals need to be specified for certain sources of funding, please add 'to initials' after the relevant agency or grant number e.g. This work was supported by the National Institutes of Health [xx456789 to C.S., yy123765 to M.H.].

References

Reference entries should be numbered consecutively in the text with the use of bracketed numerals and listed in the same order at the end of the paper. Sources should be properly referenced, indicating the author(s) name, initials, the title of the source article, journal or book, volume and issue, year of source publication, initial page number to end page number.

Examples:

Published papers

One author

Rao G. Preventing a pharma crash: A 30,000 foot view. PDA J Pharm Sci Technol. 2015; 69(6):666.

Two to five authors

Babalonis S, Hampson AJ, Lofwall MR, Nuzzo PA, Walsh SL. Quinine as a potential tracer for medication adherence: A pharmacokinetic and pharmacodynamic assessment of quinine alone and in combination with oxycodone in humans. J Clin Pharmacol. 2015; 55(12):1332–1343.

More than five authors

Morita J, Tanaka M, Nomoto M, Matsuki S, Tsuru T, et al. Pharmacokinetic bioequivalence, safety, and immunogenicity of DMB-3111, a trastuzumab biosimilar, and trastuzumab in healthy Japanese adult males: results of a randomized trial. BioDrugs. 2016; 30(1):17-25.

Note: Please list the first five authors and then add “et al.” if there are additional authors.

Electronic publications

Kielbasa W, Lobo E. Pharmacodynamics of norepinephrine reuptake inhibition: Modeling the peripheral and central effects of atomoxetine, duloxetine, and edivoxetine on the biomarker 3,4-dihydroxyphenylglycol in humans. J Clin Pharmacol. 2015; 55(12):1422–1431. doi: 10.1002/jcph.551

Tables

The table title should be concise, not more than one sentence. The rest of the table legend and any footnotes should be placed below the table. Footnotes can be used to explain abbreviations.

• Each table must be mentioned at least once in the text. Every table must have a title, and all columns must have headings.
• Column headings must be arranged so that their relation to the data is clear and refer to column below.
• Footnotes should be indicated by superscript, lowercase letters.
• Avoid tables created with the tab key, pictures, and embedded objects.

Figures

The figures should not duplicate text or one another and must be self-explanatory, if a table or figure has been published before, the author should acknowledge the original source of a previously published or adapted figures and submit written permission from the copyright holder to reproduce the material.

• Each figure must be mentioned at least once in the text, and in proper numerical order.
• Clearly mark orientation on figure, if questionable.
• Figure legends should clearly and concisely label and explain figures and parts of figures.

Multimedia submissions

Multimedia files can be included in the published papers of our journals. These multimedia files can be viewed by simply clicking on a link in the manuscript.

Authors should follow the guidelines for submission:

• Cover letter should be included that multimedia materials are uploaded as part of the submission.
• File sizes should be as small as possible.
• Provide a short description of the multimedia materials in the main body of the manuscript and it should be referred by their figure number.
• For each multimedia file, provide a figure, which is a static representation of the multimedia file. Also provide an accompanying caption. At the end of the caption, include the phrase, "(enhanced online)".
• Video and other enhanced files should be in a format that the majority of readers can view without too much difficulty.

Supplemental material

It is supplementary information for publication alongside the article. The submission of supplemental material that enhances the understanding of the biomedical science discussed in the manuscript is encouraged. Every supplemental figure, table, movie, or data file must be referred to specifically in the main text. All supplemental material must be approved by the administrator or journal editor as part of a manuscript's normal review cycle.

Prepare list of reviewers

Authors are highly encouraged to provide three or more potential reviewers contact details (including e-mail addresses) for their research paper. Reviewers should be experts in their field of research work, who will be able to provide an objective assessment of the research paper. Any suggested reviewers should not have published with any of the authors of the research paper within the past four years and should not be members of the same research institution. Members of the Editorial Board of the journal can be nominated. Suggested reviewers will be considered alongside potential reviewers identified by their publication record or recommended by Editorial Board members.

Abbreviations and symbols

Use only standard abbreviations but not nonstandard abbreviations, which may be confusing to readers. Avoid abbreviations in the title of the manuscript. The spelled-out abbreviation followed by the abbreviation in parenthesis should be used on first mention unless the abbreviation is a standard unit of measurement.

Manuscript Submission Checklist

Manuscript must follow the advice given in our Instructions to Authors. The authors must ensure that before submitting the manuscript for publication, they have taken care of the following:

• 1. Covering Letter to the Editor/ Editor-in-Chief of the Journal.
• 2. Title page should contain title, name of the author/co-authors, affiliations, email address, phone & fax number and complete corresponding author details including postal address.
• 3. Abstract in structured format and References mentioned as stated in the Instruction to Authors section.
• 4. Tables should be on separate pages. Make sure for Headings of Tables, their numbers and captions of illustrations.
• 5. Figures and photographs illustrations with high resolution and along with their captions.
• 6. Disclosure regarding source of funding and conflict of interest if any besides approval of the study from respective Ethics Committee/Institution Review Board.

Submit your Manuscript

Manuscript must be accompanied by a covering letter to the Editor/ Editor-in-Chief, including title and author(s) name and undertaking that it has not been published or submitted elsewhere.

Cover Letter Includes:

• An introduction stating the title of the manuscript and name of the journal.
• The reason why your study is important and relevant to the journal’s readership or field.
• The most important conclusions that can be drawn from your research.
• A statement that all authors approved the manuscript and its submission to the journal.

Manuscripts should be submitted electronically through our website:

http://nobleresearch.org/Noble/SubmitManuscript Or as an email attachment to the editorial office at editor.jcpt@nobleresearch.org.

To submit online, please follow on screen instructions and steps to upload different part of your article at the submission system of website. All figures, pictures, graphics or images must be submitted as supplementary files in a format of JPEG, GIF or TIFF which will produce high quality images in the online edition of the journal.

Submission of a manuscript is a representation that the paper has not been previously submitted in any publication elsewhere or published in any open literature. It also represents that the author(s) have not assigned or transferred copyright for the material.

Manuscript must be accompanied by a covering letter to the Editor-in-Chief, including title and author(s) name and undertaking that it has not been published or submitted elsewhere.

Peer-Review Process

Peer-review is commonly accepted as an essential part of scientific publication. We appreciate the time that referees devote to assessing the manuscripts we send them, which helps to ensure that NobleResearch Group journals publish only material of the highest quality. Peer reviewers are asked to give their opinion on a number of issues pertinent to the scientific and formal aspects of a paper, and to judge the papers on grounds of originality and urgency. All relevant information will be forwarded to the author (s). There are several types of decision possible for each article.

• Accept manuscript without revision
• Accept after minor or major revision
• Submit elsewhere, if the manuscript is better suited for another journal in our group
• Reject manuscript, if the manuscript is substandard

In addition, papers may be rejected directly by the Chief Editor if judged to be out of scope or if scientifically or formally sub-standard. When asking for revisions, reviewers have two possible goals: to ask authors to tighten their arguments based on existing data, or to identify areas where more data are needed. Even formal revision may be required if the language or formalities is sub-standard. To facilitate rapid publication, authors are given a maximum of two months for revision. After two months, revised manuscripts will be considered as new submissions.

Publication Process

Accepted articles are edited by copy editors and checked by NobleResearch Publishers team and once formatting is complete, authors are then asked to check their author proofs and supply corrections if required. After complete corrections, articles are displayed as articles in press and then published monthly in respective journals.

Article Processing Charges

NobleResearch Journals are an open access publications. When publishing in any NobleResearch journals, authors retain the copyright of their articles, which are freely distributed under the “Creative Common Attribution License,” permitting the unrestricted use, distribution, and reproduction of the article in any medium, provided the original work is properly cited. In order to cover the costs of the publishing operation, NobleResearch journals require article processing charges for all accepted manuscripts. After acceptance of the manuscript, the authors are requested to pay GBP (£) 400 for processing, handling and publishing charges. All articles published in NobleResearch are freely available to all readers giving authors the broadest distribution of their research possible.

Waivers may be available for certain authors, for example, from low gross domestic product (GDP) countries.

For more information about Article Processing Charges, please contact us at payments@nobleresearch.org.